Group Members

View Current Members or Alumni

Principal Investigator

 

Silvia Cavagnero

cavagnero@chem.wisc.edu
Telephone Number: Tel: (608) 262-5430. Fax: (608) 262-9918
Address: Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Room # 5351, Madison, WI 53706.

Education:
Ph.D. 1996, California Institute of Technology
M.S. 1990, University of Arizona
B.S. 1988, 'La Sapienza' University, Rome, Italy

Teaching:
-Biophysical Chemistry (Chem/Biochem 565/665)
-Biophysical Spectroscopy (Chem 668)
-Physical Chemistry (Chem561)
-Principles of Multidimensional NMR Spectroscopy (Chem 860)
-General Chemistry (Chem 103, Chem 104)
-Physical Chemistry Laboratory (Chem 563, 564, 567)

Hobbies / Interests:
Drawing, painting, curved origami, and spending time with Irene & Cecilia

Research Scientist

 

Valeria Guzman-Luna

vguzman.luna@gmail.com

Education:
B.S. 2005, National Autonomous University of Mexico (UNAM), Mexico City, Mexico
Ph.D. 2012, National Autonomous University of Mexico (UNAM), Mexico City, Mexico

Joined Group:
January, 2019 (Research Scientist)

January, 2014 (Postdoctoral Researcher)

Home Town:
Mexico city, Mexico

Research before joining the lab:
Studies on the protein folding in vitro, protein stability and protein directed evolution

Current research Project:

Cotranslational protein folding studies using fluorescence.

Interactions between ribosome nascent chains and the ribosome surface.

Hobbies / Interests:
Playing soccer, yoga and meditation.

Graduate Students

  Miranda

Miranda Mecha

mmecha@wisc.edu

Joined Group:
September, 2015

Education:
B.S. in Biochemistry at Carroll University

Home Town:
Milwaukee, Wi

Research before joining the lab:
Studying the mechanism of RNAP’s open complex formation fia FRET and  hydroxyl-radical footprinting.

Current research Project:

Determining the folded state of SH3 as it is released from DnaK using steady state and time-resolved fluorescence signal and fluorescence anisotropy, as well as stopped-flow fluorescence and Circular Dichroism (CD).

Hobbies / Interests:
Reading, reviewing books, baking, spending time with my dog.

 

Hanming Yang

hyang366@wisc.edu

Joined Group:
November, 2016

Education:
B.S. Chemistry, University of Colorado-Boulder, Boulder, CO

Research before joining the lab

High-resolution IR spectroscopy of small, organic radicals

Current Project

Sensitivity enhancement in NMR spectroscopy using Photochemically Induced Dynamic Nuclear Polarization (photo-CIDNP)

Hobbies / Interests: 

Cycling, Skiing, cat petting

 

Rachel Hutchinson

rhutchinson3@wisc.edu

Joined Group:
November, 2017

Education:
B.S. in Chemistry and Mathematics at Roberts Wesleyan College

Home Town:
Cortland, NY

Research before joining the lab:
-Studied the absorption of CdTe quantum dots onto TiO2 films (Dr. David Watsons's lab, Universiity of Buffalo)
-Compared activities of pyridine-carboxylate iridium catalysts for water oxidation (Dr. Alceo MMacchioni's lab, University of Perugia, Italy)
 

Current Research Project:
Single molecule FRET to study co-translational protein folding on the ribosome.

Hobbies / Interests:
Running and reading

 

Meranda Masse

mmasse@wisc.edu

Joined Group:
November, 2017

Education:
B.S. Chemistry and Environmental Science, Alverno College, Milwaukee, WI

Home Town:
Antioch, Illinois

Previous research before joining the lab:
Studied the relationship between microbial sulfur metabolism and Iron (III) reduction to elucidate the evolutionary history and biodiversity of microbial respiratory systems

Current Project:
Studying the thermodynamic interplay between ribosomes and nascent chains and solving high-resolution structures of RNC's using single-particle cryo-electron microscopy.

Hobbies / Interests: 
Yoga, rock climbing, reading and biking. I also have two dogs (Lincoln and Toby) that I love to spend time with.

Room Number: 5371
 

Justin Dang

hhdang@wisc.edu

Room Number: 5371

Joined Group:
December, 2019

Education:
B.S. Chemistry and Mathematics, Stetson University, Deland, FL.

Home Town:
Ho Chi Minh City, Vietnam

Previous research before joining the lab:
Investigating the role of Src-Kinase in rapid endocytosis in mouse hippocampal tissues with fluorescence optical imaging (Dr. Jianhua Xu Lab, Department of Neuroscience, Augusta University).

Current Project:
Elucidation of A Kinetically Trapped Native-Liked Conformation of Apomyoglobin under Physiologically Relevant Conditions.

Hobbies / Interests: 
Running, cooking different culture cuisines, trying out different hair colors, anime, Đam and Kpop.

Undergraduate Students

 

Jasmine Machhi

machhi2@wisc.edu

Education:

Joined Group:
January, 2020

Home Town:
Mequon, Wisconsin

Current research Project:

Studying the conformational changes client proteins experience through the molecular chaperone cycle 

Hobbies / Interests:
Traveling, music, and reading.

 

Wanting Wei

wwei54@wisc.edu

Education:

Joined Group:
June, 2019

Home Town:
Beijing, China

Current research Project:

Exploring nascent chain interactions with the ribosomal surface.

Hobbies / Interests:
Cooking and playing with pets.

 

Gordon Winkler

glwwinkler19@gmail.com

Education:

Joined Group:
January, 2020

Home Town:
Truro, Massachusetts.

Current research Project:

Kinetic trapping in eukaryotic cells.

Hobbies / Interests:
Sailing and skiing.

 

Ningkun Zhou

nzhou36@wisc.edu

Education:

Joined Group:
January, 2020

Home Town:
Huizhou, China

Current Research Project:

Studying ribosome-bonded proteins chains by using single-molecule fluorescence.

Hobbies / Interests:

traveling, movie, music

 

Kevin England

kengland@wisc.edu

Joined Group:
January, 2018

Education:

Current Project:

Investigating protein thermostability 

Hobbies / Interests:

Canoeing, backpacking, skiing

 

Anna Allen

ajallen2@wisc.edu

Joined Group:
January, 2019

Education:

Current research project:

Reengineering the E. coli ribosome to reduce inclusion body formation in overexpression conditions. 

Hobbies / Interests:

Running, traveling, music, foreign languages

 

 

 

 

Chelsea Chen

xchen783@wisc.edu

Joined Group:
January, 2019

Education:

Current research project:

Viscosity measurements to study compaction of ribosome-bound nascent peptide chains.

Hobbies / Interests:

Traveling, running, trying new food, calligraphy and photography.